As an osteopathic physician with an interest in the intersection of osteopathy and psychedelic medicine, I’m excited to share the latest updates in the field of psychedelic research and therapy. Our holistic approach to patient care aligns well with the potential of psychedelics to address both mental and physical health concerns.
Research Developments
Recent studies have shown promising results for psychedelic-assisted therapies in treating various conditions. A study published in Nature Mental Health revealed that psilocybin, when combined with psychotherapy, significantly reduced anxiety, depression, and other psychological symptoms in cancer patients, with improvements lasting up to six months[6]. Another study found that psilocybin treatment led to lasting, positive personality changes in patients with alcohol use disorder[6].
These findings are particularly intriguing from an osteopathic perspective, as they demonstrate the potential for psychedelics to address the mind-body connection we emphasize in our practice.
Clinical Trials and FDA Approval
While 2024 saw some setbacks, including the FDA’s rejection of Lykos Therapeutics’s MDMA-based depression treatment, the psychedelic medicine industry is recalibrating for future success[1]. Several companies are currently conducting Phase 3 trials:
– Compass Pathways: Testing psilocybin for treatment-resistant depression
– Usona Institute: Investigating psilocybin for major depressive disorder
– Awakn Life Sciences: Exploring ketamine for alcohol use disorder
– MindMed: Studying LSD for generalized anxiety disorder
As physicians, we should keep an eye on these trials, as they may lead to new treatment options for our patients in the coming years.
Neuroplasticity and Mechanism of Action
Emerging evidence suggests that psychedelics may increase human neuroplasticity, which could be their primary mechanism of action[2]. This aligns well with osteopathic principles, as we often focus on the body’s ability to heal itself and adapt to change.
Upcoming Events
For those interested in staying at the forefront of psychedelic research, two major conferences are scheduled for 2025:
1. The 5th Annual Psychedelic Therapeutics and Drug Development Conference in San Diego, CA (May 19-20, 2025)[3]
2. Psychedelic Science 2025 in Denver, CO (June 16-20, 2025)[5]
These events offer excellent opportunities to network with colleagues and learn about the latest advancements in the field.
As osteopathic physicians, we’re uniquely positioned to integrate psychedelic therapies into our holistic approach to patient care. By staying informed about these developments, we can better serve our patients and contribute to the evolving landscape of mental health treatment.
Citations:
[1] https://www.healthcare-brew.com/stories/2025/01/13/2025-psychedelic-use-healthcare
[2] https://www.psychiatryonline.org/doi/10.1176/appi.pn.2025.01.1.14
[3] https://psychedelics-conference.com
[4] https://clinicaltrials.ucsf.edu/psilocybin
[5] https://maps.org/2024/02/13/psychedelic-science-2025-save-the-date/
[6] https://www.sciencedaily.com/releases/2025/01/250102162637.htm
[7] https://www.apa.org/monitor/2025/01/trends-psychedelic-treatments
The Psychedelic Osteopath 